The role of transforming growth factor-ß (TGF-ß1) in postmenopausal women with pelvic organ prolapse: An immunohistochemical study
نویسندگان
چکیده
منابع مشابه
Maternal Serum Levels of Transforming Growth Factor ß1 (TGF-ß1) in Normal and Preeclamptic Pregnancies
Background: Successful pregnancy in allopregnant women depends upon the control of graft rejection mechanisms. It has been suggested that some immunosuppressive cytokines contribute to successful pregnancy and transplantation. Transforming growth factor beta (TGF- β) exhibits potent immunoregulatory and anti-inflammatory properties which might prolong graft survival. Recent studies suggest a ...
متن کاملExpression of transforming growth factor-beta 1 and connective tissue growth factor in women with pelvic organ prolapse.
OBJECTIVE To investigate the presence of transforming growth factor-beta 1 (TGF-ß1) and connective tissue growth factor (CTGF) in women with pelvic organ prolapse (POP). METHODS This study was conducted from May to December 2009. Fifty patients with POP that underwent vaginal hysterectomy in the Department of Gynecology, Renmin Hospital of Wuhan University, Hubei, Wuhan, China were enrolled i...
متن کاملRe: Sexual function in women with pelvic organ prolapse compared to women without pelvic organ prolapse.
PURPOSE We compared sexual function in women with pelvic organ prolapse to that in women without prolapse. MATERIALS AND METHODS We collected sexual function data using a standardized, validated, condition specific questionnaire. The study group consisted of 30 women with pelvic organ prolapse and it was compared with 30 unmatched controls without evidence of prolapse. RESULTS The 2 groups ...
متن کاملmaternal serum levels of transforming growth factor ß1 (tgf-ß1) in normal and preeclamptic pregnancies
background: successful pregnancy in allopregnant women depends upon the control of graft rejection mechanisms. it has been suggested that some immunosuppressive cytokines contribute to successful pregnancy and transplantation. transforming growth factor beta (tgf- β) exhibits potent immunoregulatory and anti-inflammatory properties which might prolong graft survival. recent studies suggest a ...
متن کاملGenetic Association Study in Women with Pelvic Organ Prolapse
Hypothesis / aims of study Pelvic organ prolapse (POP) is a common yet distressing pelvic floor dysfunction affecting one-third of adult women worldwide. However, the underlying pathophysiology is largely unknown. Its etiology is multifactorial, including direct mechanical injury, partial denervation of pelvic floor, and hormonal changes caused by pregnancy. Findings from epidemiologic studies ...
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ژورنال
عنوان ژورنال: European Journal of Obstetrics & Gynecology and Reproductive Biology: X
سال: 2020
ISSN: 2590-1613
DOI: 10.1016/j.eurox.2020.100111